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A man from Manchester and two from Liverpool have been arrested in Ibiza.
They are among nine Britons who have been arrested during drugs raids on the Spanish island.
Eight addresses were searched in the joint operation between Spanish authorities and the UK's Serious Organised Crime Agency.
Large quantities of cocaine, hashish, ecstasy and MDMA powder, cash and equipment were seized during the raids, which were targeting alleged trafficking networks.
The majority of the pills seized are known as Pink Rock Star and are similar to those believed to have caused the death of a young British girl and poisoned eight others in July.
A total of 13 people were arrested.