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31 May 2012, 18:41 | Updated: 30 March 2016, 13:50
The drug called 4-Methylamphetamine was found in York in a paste form.
It is visually similar to amphetamine but this is the first time it has been seized in the county.
A man from York has been arrested and is currently on bail while police enquiries continue.
DC Louise Taylor, a Drug Liaison Officer at North Yorkshire Police, said:
"I am concerned that users will be unaware that they are taking this drug, believing it to be amphetamine. As a result they will not be fully aware of the risks involved. Regular users of amphetamine may not be able to distinguish between this drug and amphetamine.
"Whilst we strongly advise people against taking this or other controlled drugs, we would advise that if they are using this substance or a drug they believe to be amphetamine, if they start to feel very unwell they should call 999 immediately and call an ambulance.