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13 January 2012, 07:20 | Updated: 13 January 2012, 07:28
The boy band are hoping to scoop the prize for a second time at next months BRITs in London.
JLS have admitted that they believe the award for Best British Single at the BRITs 2012 is the most important award.
The 'Do You Feel What I Feel' band confessed that it is "amazing" to be nominated again and hope to take home the award for the second time.
Speaking to Capital FM's Rich Clarke, Marvin said: "[It's] the most important award I would say.
"For us you know obviously we won the award two years ago [with] 'Beat Again', so for us to be back here again in 2012 with 'She Makes Me Wanna' – a song that we've written ourselves, is just amazing. Fingers crossed we might win it again."
The boy band will go up against the likes of One Direction, Example, Jessie J and Olly Murs at the O2 Arena in London, the shortlist being made up of the acts with the most amount of commercial radio air play and sales in 2011.
Voting is now open for the British Single category.
The winner of this prestigious award will be as a result of your votes, and they will collect their prize when the BRITs take place at London's O2 Arena on 21st February.
Everyone who votes will be entered into a competition to win a pair of tickets to this year's BRIT Awards – please see the terms and conditions.
Find out more details, including the latest news, photos and interviews, about this year's ceremony, as well as a round-up of all the nominees, in our BRIT Awards area.
Adele – 'Someone Like You'
Ed Sheeran – 'The A Team'
Example – 'Changed The Way You Kiss Me'
Jessie J ft. B.o.B – 'Price Tag'
JLS ft. Dev – 'She Makes Me Wanna'
Military Wives with Gareth Malone – 'Where You Are'
Olly Murs ft. Rizzle Kicks – 'Heart Skips A Beat'
One Direction – 'What Makes You Beautiful'
Pixie Lott – 'All About Tonight'
The Wanted – 'Glad You Came'