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17 December 2012, 09:21 | Updated: 17 December 2012, 09:23
'Live While We're Young' band One Direction and US stars Maroon 5 were also honoured in the year-end awards.
Adele has been named Billboard's top artist of the 2012 as well as winning top album of 2012 for her second record '21', making her the first artist to do so in two consecutive years.
The 'Rolling In The Deep' singer also won both awards back in 2011, again for her hugely successful album '21', and remains the publication's top artist of the year after continued high sales of the record.
Adele was also named Billboard's top female artist, giving her three new awards in total, while 'Take Care' rapper Drake received the top male artist gong.
One Direction have also been honoured after being named the top new act of 2012 while 'Moves Like Jagger' band Maroon 5 were named best group.
The publication also gave Gotye's 'Somebody That I Used To Know' the accolade of top song of 2012, followed by Carly Rae Jepsen's 'Call Me Maybe' and Fun.'s 'We Are Young'.
Check out a picture of Adele performing at the BRITs 2012 earlier this year below (Credit: Getty):
British band The Wanted's debut US release 'Glad You Came' came sixth on the list while One Direction's 'What Makes You Beautiful' was at number ten.
Adele has had a successful past two weeks after it was announced her James Bond theme 'Skyfall' is up for a Golden Globe next year as well as being shortlisted for the Oscars Original Song nominations.