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Greater Manchester Police have renewed an appeal to find a family from Manchester a year since they disappeared.
31 year old Anisa Ibrahim from Withington, and her two children, Khalid, 5, and Ahmed Abubakar, 4, were reported missing by the boys father Abdul Abubakaron the 6th April 2010.
It's thought they took a coach to Amsterdam and may have travelled onwards to another country.
Police are concerned for the welfare of the children, particularly Khalid, who has a severe skin condition which requires medical attention.
Detective Inspector Kevin Marriott from South Manchester CID, said: "I am appealing to the Somalian community worldwide to come forward with any information on the whereabouts of the children and Anisa.
"This investigation has continued throughout the past year and we will not give up hope of finding Anisa and her children.
"The father of the children is very upset and concerned for his two boys.
"If anyone has seen them or knows where they are, please contact us - any information passed to police can be treated in the strictest of confidence."
Anyone with information is asked to contact Greater Manchester Police on 0161 872 5050 quoting MP/10/46672, officers in south Manchester on 0161 856 6104 or the independent charity, Crimestoppers, anonymously, on 0800 555 111.